Biomineralization-mimetic preparation of robust metal-organic frameworks biocomposites film with high enzyme load for electrochemical biosensing

Inspired by biomineralization, we propose robust enzyme-metal-organic-frameworks (MOFs) biocomposites to fabricate ultra-stable modified-electrode for electrochemical biosensing. Glucose oxidase (GOx) and zeolitic imidazolate framework-8 (ZIF-8) were adopted as model enzyme and MOFs to illustrate and examine the proposed concept. The biocomposites could be readily prepared by mixing GOx and precursors of MOFs. The biomineralization-assisted...