Association of BRCA2 variants with breast cancer risk: A meta-analysis

BRCA2 is a tumor suppressor gene involved in repair of double strand breaks in DNA. Germ line mutations within this gene are implicated in familial breast and ovary cancer syndromes. Moreover, several studies have assessed association between single nucleotide polymorphisms (SNPs) within this gene and risk of breast cancer. We performed a meta-analysis to assess the association between rs4987117, rs1799955, rs766173, rs15869 SNPs within BRCA2...