Akt, mTOR and NF-κB pathway activation in Treponema pallidum stimulates M1 macrophages

Volume: 59, Pages: 181 - 186
Published: Jun 1, 2018
Abstract
The polarization of macrophages and the molecular mechanism involved during the early process of syphilis infection remain unknown. This study was conducted to explore the influence of Treponema pallidum (T. pallidum) treatment on macrophage polarization and the Akt-mTOR-NFκB signaling pathway mechanism involved in this process. M0 macrophages derived from the phorbol-12-myristate-13-acetate-induced human acute monocytic leukemia cell line THP-1...
Paper Details
Title
Akt, mTOR and NF-κB pathway activation in Treponema pallidum stimulates M1 macrophages
Published Date
Jun 1, 2018
Volume
59
Pages
181 - 186
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