Coumarins improved type 2 diabetes induced by high-fat diet and streptozotocin in mice via antioxidation

Volume: 96, Issue: 8, Pages: 765 - 771
Published: Apr 11, 2018
Abstract
Coumarins extensively exist in plants and are utilized against diabetes in some folk medicines. Recent studies have demonstrated that oxidative stress plays a crucial role in the etiology and pathogenesis of diabetes mellitus. We investigated the antioxidant ability of 3 coumarins (osthole, esculin, and fraxetin) in type 2 diabetes. After being fed a high-fat diet, ICR mice were exposed to low doses of streptozotocin and then treated with...
Paper Details
Title
Coumarins improved type 2 diabetes induced by high-fat diet and streptozotocin in mice via antioxidation
Published Date
Apr 11, 2018
Volume
96
Issue
8
Pages
765 - 771
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