Glucose Lowering Strategies for Cardiac Benefits: Pathophysiological Mechanisms
Abstract
Recent trials in Type 2 diabetes (T2D) have shown cardiovascular benefits with specific GLP-1 receptor agonists and SGLT2 inhibitors. We discuss the landscape of outcome trials in T2D from a pathophysiology viewpoint, review current knowledge gaps in underlying mechanisms, propose a caloric fuel routing hypothesis, and highlight areas of future...
Paper Details
Title
Glucose Lowering Strategies for Cardiac Benefits: Pathophysiological Mechanisms
Published Date
May 1, 2018
Journal
Volume
33
Issue
3
Pages
197 - 210
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