Quality evaluation of the artemisinin-producing plant Artemisia annua L. based on simultaneous quantification of artemisinin and six synergistic components and hierarchical cluster analysis

Artemisia annua L. (A. annua) is one of the most widely used traditional Chinese Medicine, and is also an exclusive natural origin of artemisinin for the industrial production. Several sesquiterpenes, flavonoids and coumarin contained in A. annua could enhance the pharmacological effects of artemisinin. However, the contents of these components vary significantly in different places of origin and different parts of A. annua. To evaluate and...