Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells
Abstract
Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of peptides in the blood, liver and kidneys. Since AuNPs seem to have a longer plasma half-life than PDCs, one approach to overcoming this problem would be to conjugate the PDCs to gold nanoparticles (AuNPs), as these have...
Paper Details
Title
Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells
Published Date
Mar 30, 2018
Journal
Volume
16
Issue
1
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