Abstract CN07-01: Cellular plasticity in cancer: Driving force and therapeutic target

Volume: 17, Issue: 1_Supplement, Pages: CN07 - 01
Published: Jan 1, 2018
Abstract
We have shown that in particular tumor cells at the invasive front undergo a partial epithelial-mesenchymal transition (EMT) and aberrantly express EMT-associated transcription factors (EMT-TFs). The amount of such cancer cells strongly correlates with metastasis formation and poor clinical outcome in human cancers. Strikingly, metastases show a mesenchymal-epithelial retransition (MET) with a redifferentiated phenotype, indicating high cancer...
Paper Details
Title
Abstract CN07-01: Cellular plasticity in cancer: Driving force and therapeutic target
Published Date
Jan 1, 2018
Volume
17
Issue
1_Supplement
Pages
CN07 - 01
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