Novel Insights into How Overnutrition Disrupts the Hypothalamic Actions of Leptin
Abstract
Obesity has become a worldwide health problem, but we still do not understand the molecular mechanisms that contribute to overeating and low expenditure of energy. Leptin has emerged as a major regulator of energy balance through its actions in the hypothalamus. Importantly, obese people exhibit high circulating levels of leptin, yet the hypothalamus no longer responds normally to this hormone to suppress appetite or to increase energy...
Paper Details
Title
Novel Insights into How Overnutrition Disrupts the Hypothalamic Actions of Leptin
Published Date
Mar 26, 2018
Journal
Volume
9
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