The five‐year survival of children with Down syndrome in Norway 1994–2009 differed by associated congenital heart defects and extracardiac malformations

Aim We investigated the prevalence of Down syndrome in a nationwide birth cohort, focusing on congenital heart defects (CHDs), their associations with extracardiac malformations (ECM) and survival. Methods National registers were used to identify Norwegian births (1994–2009) and deaths (1994–2014) and updated with hospital diagnoses. We estimated birth defect frequencies in Down syndrome and the general population, the association between CHDs...