Determination of the limit of detection for iodinated contrast agents with multi-energy computed tomography

Multiple studies in the literature have proposed diagnostic thresholds based on Multi-Energy Computed Tomography (MECT) iodine maps. However, it is critical to determine the minimum detectable iodine concentration for MECT systems to assure the clinical accuracy for various measured concentrations for these image types. In this study, seven serial dilutions of iohexol were made with concentrations from 0.03 to 2.0 mg Iodine/mL in 50 mL...