Comparative In Vitro Activity of Omadacycline against Dog and Cat Bite Wound Isolates.

Published on Mar 27, 2018in Antimicrobial Agents and Chemotherapy5.191
路 DOI :10.1128/AAC.02551-17
Ellie J. C. Goldstein66
Estimated H-index: 66
(UCLA: University of California, Los Angeles),
Diane M. Citron57
Estimated H-index: 57
+ 2 AuthorsC. Vreni Merriam26
Estimated H-index: 26
: Omadacycline was tested against 125 isolates recovered from infected cat and dog bites in humans. Its activity was similar to that of other compounds in the tetracycline class, and it was active against strains exhibiting tetracycline resistance. Against anaerobic isolates, resistance to tetracyclines was more prominent and omadacycline was the most active of the group. All isolates had omadacycline MICs of <1 渭g/ml, with the exception of Eikenella corrodens, which showed reduced susceptibility to the entire tetracycline group.
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