ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection.
Abstract
Ischemia-reperfusion (IR) injury is central to the pathology of major cardiovascular diseases, such as stroke and myocardial infarction. IR injury is mediated by several factors including the elevated production of reactive oxygen species (ROS), which occurs particularly at reperfusion. The mitochondrial respiratory chain and NADPH oxidases of the NOX family are major sources of ROS in cardiomyocytes. The first part of this review discusses...
Paper Details
Title
ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection.
Published Date
Mar 1, 2018
Volume
117
Pages
76 - 89
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