The fully‐extended conformation in peptides and proteins

The intramolecularly H‐bonded, fully‐extended conformation (C 5 ) of an α‐amino acid residue (and the resulting 2.0 5 ‐helix obtained via its propagation) is one of the least extensively investigated types of peptide and protein backbone secondary structure. This situation does still currently occur despite its unique ability to enjoy by far the largest separation per residue among peptide conformations. In this article, we offer a detailed...