Bio-guided isolation of Centaurea bruguierana subsp. belangerana cytotoxic components
Abstract
Centaurea bruguierana subsp. belangerana was extracted by 80% ethanol. The total extract was then partitioned into four fractions including chloroform, ethyl acetate and methanol. Cytotoxic effect of fractions was examined by MTT assay in K562 (chronic myelogenous leukemia), AGS (gastric adenocarcinoma), MCF-7 (breast adenocarcinoma) and SW742 (colon adenocarcinoma) cell lines. The Chloroform fraction, with the lowest LC50 against K-562 cell...
Paper Details
Title
Bio-guided isolation of Centaurea bruguierana subsp. belangerana cytotoxic components
Published Date
Feb 19, 2018
Journal
Volume
33
Issue
11
Pages
1687 - 1690
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