The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
Abstract
Cytokines and hormones, including insulin, are known to modulate the hypothalamic-pituitary-testes axis and steroidogenesis, both centrally and peripherally. In the context of chronic inflammation and hyperinsulinaemia mediating male hypogonadism associated with obesity, metabolic syndrome and type 2 diabetes mellitus, these mechanisms are poorly understood and the impact of cytokines and insulin on Leydig cell steroidogenesis has not been fully...
Paper Details
Title
The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
Published Date
Mar 22, 2018
Volume
16
Issue
1
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