Can profiles of poly- and Perfluoroalkyl substances (PFASs) in human serum provide information on major exposure sources?

Xindi C. Hu; Clifton Dassuncao; Xianming Zhang; Philippe Grandjean; Pal Weihe; Glenys M. Webster; Flemming Nielsen; Elsie M. Sunderland

doi:https://doi.org/10.1186/s12940-018-0355-4

doi.org/10.1186/s12940-018-0355-4

Can profiles of poly- and Perfluoroalkyl substances (PFASs) in human serum provide information on major exposure sources?

,

,

..., Elsie M. Sunderland

53

Environmental Health6.00

Volume: 17, Issue: 1

Published: Feb 1, 2018

Abstract

Humans are exposed to poly- and perfluoroalkyl substances (PFASs) from diverse sources and this has been associated with negative health impacts. Advances in analytical methods have enabled routine detection of more than 15 PFASs in human sera, allowing better profiling of PFAS exposures. The composition of PFASs in human sera reflects the complexity of exposure sources but source identification can be confounded by differences in toxicokinetics...