Plasma metabolomics coupled with MetaboAnalyst and Ingenuity Pathway Analysis characterizes linoleic acid metabolism disorder in patients with spleen-yang-deficiency syndrome

Spleen-yang-deficiency syndrome (SYDS) is a hot spot pattern in gastroenterology in traditional Chinese medicine (TCM) clinic and has received increasing attention from clinicians because it is closely related to diseases of diarrhoea, irritable bowel syndrome, myasthenia and gastric cancer, etc. Although the symptom-based diagnostic criteria for SYDS have been suggested, the real causes are still unclear. In this current study, metabolic...