Brain lactate and pH in schizophrenia and bipolar disorder: a systematic review of findings from magnetic resonance studies

Volume: 43, Issue: 8, Pages: 1681 - 1690
Published: Mar 14, 2018
Abstract
Converging evidence from molecular to neuroimaging studies suggests brain energy metabolism abnormalities in both schizophrenia and bipolar disorder. One emerging hypothesis is: decreased oxidative phosphorylation leading to accumulation of lactic acid from glycolysis and subsequent acidification of tissue. In this regard, integrating lactate and pH data from magnetic resonance spectroscopy (MRS) studies in both diseases may help us understand...
Paper Details
Title
Brain lactate and pH in schizophrenia and bipolar disorder: a systematic review of findings from magnetic resonance studies
Published Date
Mar 14, 2018
Volume
43
Issue
8
Pages
1681 - 1690
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