The impaired proteases and anti-proteases balance in Idiopathic Pulmonary Fibrosis.
Abstract
Idiopathic Pulmonary Fibrosis (IPF) is a devastating chronic, progressive and irreversible disease that remains refractory to current therapies. Matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitors of MMPs (TIMPs), have been implicated in the development of pulmonary fibrosis since decades. Coagulation signalling deregulation, which influences several key inflammatory and fibro-proliferative responses, is also essential in...
Paper Details
Title
The impaired proteases and anti-proteases balance in Idiopathic Pulmonary Fibrosis.
Published Date
Mar 6, 2018
Journal
Pages
382 - 403
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Notes
History