Maternal androgen excess and obesity induce sexually dimorphic anxiety‐like behavior in the offspring

Volume: 32, Issue: 8, Pages: 4158 - 4171
Published: Mar 22, 2018
Abstract
Maternal polycystic ovary syndrome (PCOS), a condition associated with hyperandrogenism, is sug-gested to increase anxiety-like behavior in the offspring. Because PCOS is closely linked to obesity, we investigated the impact of an adverse hormonal or metabolic maternal environment and offspring obesity on anxiety in the offspring. The obese PCOS phenotype was induced by chronic high-fat-high-sucrose (HFHS) consumption together with prenatal...
Paper Details
Title
Maternal androgen excess and obesity induce sexually dimorphic anxiety‐like behavior in the offspring
Published Date
Mar 22, 2018
Volume
32
Issue
8
Pages
4158 - 4171
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