New Causes for the Old Problem of Bile Reflux Gastritis

Bile reflux gastritis (also known as “duodenogastric reflux,” “biliary gastritis,” or “alkaline reflux gastritis”) occurs when there is retrograde movement of bile into the stomach, leading to clinical symptoms, endoscopic changes, and histologic features of a chemical (reactive) gastritis. Although William Beaumont first observed bile reflux in a patient with a gastrocutaneous fistula in 1833,1Beaumont W. Experiments and observations on the...