Multicomponent domino synthesis of 2-(tert-butyl)-4H-pyran-3-carbonitriles and their photophysical properties

A concise and efficient one-pot synthetic method toward functionalized pyrans has been developed. Multicomponent domino reaction proceeds by mixing aromatic aldehyde, pivaloylacetonitrile, and (E)-N-methyl-1-(methylthio)-2-nitroethen-1-amine in the presence of NH4OAc under microwave irradiation in ethanol. This method was used to synthesize 13 new compounds. The structures of the compounds were confirmed by 1H and 13C NMR, IR, and ESI-MS. The...