Clear cell carcinomas of the ovary and kidney: clarity through genomics
Abstract
Clear cell ovarian carcinoma (CCOC) and clear cell renal cell carcinoma (ccRCC) both feature clear cytoplasm, owing to the accumulation of cytoplasmic glycogen. Genomic studies have demonstrated several mutational similarities between these two diseases, including frequent alterations in the chromatin remodelling SWI-SNF and cellular proliferation phosphoinositide 3-kinase-mammalian target of rapamycin pathways, as well as a shared hypoxia-like...
Paper Details
Title
Clear cell carcinomas of the ovary and kidney: clarity through genomics
Published Date
Feb 23, 2018
Journal
Volume
244
Issue
5
Pages
550 - 564
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