Systematic review of outcome measures following chemoradiotherapy for the treatment of anal cancer (CORMAC)

Aim Six Phase III randomized trials have determined the effectiveness of chemoradiotherapy as primary treatment for anal squamous cell carcinoma ( ASCC ), but outcomes reported in these trials varied widely, hindering evidence synthesis. To improve reporting in all future trials, we aim to develop a core outcomes set ( COS ). As the first stage of COS development, we undertook a systematic review to summarize the outcomes reported in studies...