G protein-coupled estrogen receptor is involved in the anti-inflammatory effects of genistein in microglia
Abstract
Genistein (GEN), a phytoestrogen that is extracted from leguminous plants, can bind to estrogen receptor and exert biological effects. G protein-coupled estrogen receptor (GPER), a novel membrane estrogen receptor, has been reported to be involved in the anti-inflammatory process. In the present study, using BV2 microglial cell line and primary microglial culture, we evaluated the involvement of GPER in the anti-inflammatory effects of genistein...
Paper Details
Title
G protein-coupled estrogen receptor is involved in the anti-inflammatory effects of genistein in microglia
Published Date
Apr 1, 2018
Journal
Volume
43
Pages
11 - 20
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