Interaction of osteoblast -TiO2 nanotubes in vitro: The combinatorial effect of surface topography and other physico-chemical factors governs the cell fate

In the context of surface modification of implants by TiO2 nanotubes, the topography of the nanotubes has been considered as a sole modulator of cellular response of adherent cells. However, a recent report has indicated about the existence of other contributing factors. Keeping this contradiction in mind, here we have performed a comprehensive study to account the contribution of the various factors such as morphological aspects, physico...