Analyte

Optics

Physics

Molecular imaging

Detection theory

Biotechnology

Calibration

Nanotechnology

Chemistry

Materials science

Programming language

In vivo

SIGNAL (programming language)

Computer science

Chromatography

Quantum mechanics

Biology

Optical imaging

Detector

Chemical Society Reviews

Conventional optical nanoprobes rely on absolute intensity-dependent signal readout, which can often cause erroneous sensing and imaging results owing to the existence of analyte-independent confounding factors. Ratiometric signal processing provides built-in self-calibration for signal correction, enabling more accurate molecular detection and imaging.

Ratiometric optical nanoprobes enable accurate molecular detection and imaging