Reversal of multidrug resistance by icaritin in doxorubicin-resistant human osteosarcoma cells
Abstract
Multidrug resistance (MDR) is one of the major obstacles in cancer chemotherapy. Our previous study has shown that icariin could reverse MDR in MG-63 doxorubicin-resistant (MG-63/DOX) cells. It is reported that icariin is usually metabolized to icariside II and icaritin. Herein, we investigated the effects of icariin, icariside II, and icaritin (ICT) on reversing MDR in MG-63/DOX cells. Among these compounds, ICT exhibited strongest effect and...
Paper Details
Title
Reversal of multidrug resistance by icaritin in doxorubicin-resistant human osteosarcoma cells
Published Date
Jan 1, 2018
Volume
16
Issue
1
Pages
20 - 28
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