Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease

Volume: 65, Pages: 201 - 205
Published: May 1, 2018
Abstract
Alzheimer's disease (AD) is known to be associated with loss of cholinergic neurons in the nucleus basalis of Meynert, located in the posterior basal forebrain. Structural changes of septal nuclei, located in the anterior basal forebrain, have not been well studied in AD. Using a validated algorithm, we manually traced septal nuclei on high-resolution coronal magnetic resonance imaging (MRI) in 40 subjects with mild cognitive impairment (MCI) or...
Paper Details
Title
Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease
Published Date
May 1, 2018
Volume
65
Pages
201 - 205
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