Chitosan‐Based Thermo/pH Double Sensitive Hydrogel for Controlled Drug Delivery
Abstract
A series of thermo/pH sensitive N ‐succinyl hydroxybutyl chitosan (NSHBC) hydrogels with different substitution degrees of succinyl are prepared for drug delivery. Rheology analysis shows that the gelation temperature of NSHBC hydrogels is 3.8 °C higher than that of hydroxybutyl chitosan (HBC) hydrogels. A model drug bovine serum albumin (BSA) is successfully loaded and released. NSHBC hydrogels show excellent pH sensitivity drug release...
Paper Details
Title
Chitosan‐Based Thermo/pH Double Sensitive Hydrogel for Controlled Drug Delivery
Published Date
Jan 25, 2018
Journal
Volume
18
Issue
3
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