Mature results of a prospective study of deintensified chemoradiotherapy for low‐risk human papillomavirus‐associated oropharyngeal squamous cell carcinoma

BACKGROUND The purpose of the current study was to determine quality of life and tumor control from a prospective phase 2 clinical trial evaluating deintensified chemoradiotherapy for favorable risk, human papillomavirus (HPV)‐associated oropharyngeal squamous cell carcinoma. METHODS Patients with T0‐T3, N0‐N2c, M0, p16‐positive disease and a minimal smoking history were treated with 60 grays of intensity‐modulated radiotherapy with concurrent...