Could early tumour volume changes assessed on morphological MRI predict the response to chemoradiation therapy in locally-advanced rectal cancer?

•An additional MRI performed during CRT may be useful in the early evaluation of response to CRT. •TRG correlated slightly better with ΔVmid (ρ=0.713, p<0.001) than ΔVpost (ρ=0.645, p<0.001). •MidMRI might be potentially useful to tailor patient’s treatment in relation to tumour shrinkage. Aim To investigate the potential role of an additional magnetic resonance imaging (MRI) examination performed during neoadjuvant chemoradiation therapy (CRT)...