Downstaging of locally advanced pancreatic cancer after multimodal treatment

Stage III pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis and no gold standard treatment has been established so far. Radiofrequency ablation (RFA) is a new treatment option for locally advanced pancreatic cancer (LAPC) but its application is still very limited. In our new protocol RFA, as cytoreductive intent, is associated with chemoradiotherapy in a multimodal setting. We evaluate the results in terms of survival, achievement of...