The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids
Abstract
Excessive consumption of sweets is a risk factor for metabolic syndrome. A major chemical feature of sweets is fructose. Despite strong ties between fructose and disease, the metabolic fate of fructose in mammals remains incompletely understood. Here we use isotope tracing and mass spectrometry to track the fate of glucose and fructose carbons in vivo, finding that dietary fructose is cleared by the small intestine. Clearance requires the...
Paper Details
Title
The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids
Published Date
Feb 1, 2018
Journal
Volume
27
Issue
2
Pages
351 - 361.e3
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Notes
History