Genome‐wide association studies in Crohn's disease: Past, present and future

Volume: 7, Issue: 1
Published: Jan 1, 2018
Abstract
Over the course of the past decade, genome-wide association studies (GWAS) have revolutionised our understanding of complex disease genetics. One of the diseases that has benefitted most from this technology has been Crohn's disease (CD), with the identification of autophagy, the IL-17/IL-23 axis and innate lymphoid cells as key players in CD pathogenesis. Our increasing understanding of the genetic architecture of CD has also highlighted how a...
Paper Details
Title
Genome‐wide association studies in Crohn's disease: Past, present and future
Published Date
Jan 1, 2018
Volume
7
Issue
1
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