Internal medicine

Enzyme

Pancreatic elastase

Biology

Microbiology

Gastroenterology

Meta-analysis

Pancreatitis

Chemistry

Exocrine pancreatic insufficiency

Elastase

Biochemistry

Feces

Medicine

Clinical Gastroenterology and Hepatology

Tests to quantify fecal levels of chymotrypsin like elastase family member 3 (CELA3 or elastase-1) in feces are widely used to identify patients with exocrine pancreatic insufficiency (EPI). However, the diagnostic accuracy of this test, an ELISA, is not clear. We performed a systematic review and meta-analysis to determine the accuracy of measurement of fecal elastase-1 in detection of EPI.

Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis