Substantia Nigra Free Water Increases Longitudinally in Parkinson Disease
Abstract
BACKGROUND AND PURPOSE:
Free water in the posterior substantia nigra obtained from a bi-tensor diffusion MR imaging model has been shown to significantly increase over 1- and 4-year periods in patients with early-stage idiopathic Parkinson disease compared with healthy controls, which suggests that posterior substantia nigra free water may be an idiopathic Parkinson disease progression biomarker. Due to the known temporal...Paper Details
Title
Substantia Nigra Free Water Increases Longitudinally in Parkinson Disease
Published Date
Feb 1, 2018
Volume
39
Issue
3
Pages
479 - 484
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