Strongly enhanced bacterial bioluminescence with the ilux operon for single-cell imaging

Volume: 115, Issue: 5, Pages: 962 - 967
Published: Jan 16, 2018
Abstract
Bioluminescence imaging of single cells is often complicated by the requirement of exogenous luciferins that can be poorly cell-permeable or produce high background signal. Bacterial bioluminescence is unique in that it uses reduced flavin mononucleotide as a luciferin, which is abundant in all cells, making this system purely genetically encodable by the lux operon. Unfortunately, the use of bacterial bioluminescence has been limited by its low...
Paper Details
Title
Strongly enhanced bacterial bioluminescence with the ilux operon for single-cell imaging
Published Date
Jan 16, 2018
Volume
115
Issue
5
Pages
962 - 967
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