Novel in situ forming hydrogel based on xanthan and chitosan re-gelifying in liquids for local drug delivery.
Abstract
null null Injectable hydrogels have been an attractive topic in biomaterials. However, during gelation in vivo, they are easy to disperse due to tissue exudates, thus leading to failure of controlled drug release. To solve this problem, we present a novel polysaccharide-based injectable hydrogel via self-crosslinking of aldehyde-modified xanthan (Xan-CHO) and carboxymethyl-modified chitosan (NOCC). The physical properties were optimized by...
Paper Details
Title
Novel in situ forming hydrogel based on xanthan and chitosan re-gelifying in liquids for local drug delivery.
Published Date
Apr 15, 2018
Journal
Volume
186
Pages
54 - 63
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