Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells.

Volume: 63, Pages: 1 - 9
Published: Mar 1, 2018
Abstract
Studies on cervical cancer are urgently required to improve clinical outcomes. As a major anticancer drug for cervical cancer, paclitaxel has been used for many years in clinical therapy but its therapeutic efficacy is limited by common obstacle from cancer cells. The enhanced DNA repair pathways of cancer cells have been proved to survive DNA damage induced by chemotherapeutic drug. Inhibitors of specific DNA repair pathway can sensitize cancer...
Paper Details
Title
Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells.
Published Date
Mar 1, 2018
Journal
Volume
63
Pages
1 - 9
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