Nanomotor‐Based Strategy for Enhanced Penetration across Vasculature Model

Here the first nanomotor‐based strategy is reported to effectively cross tumor vasculature endothelium. The designed nanomotors are based on (poly(ethylene glycol)‐ b ‐polystyrene and poly(acrylic acid)‐ b ‐polystyrene) building blocks, which further self‐assemble into polymersomes of tunable sizes (100, 300 nm). The polymersomes are readily loaded with hydrophilic model drug into the aqueous compartment. A catalytic platinum cap is then...