757: Impact of a dietary intervention and maternal factors during pregnancy on DNA methylation in 5-year-old offspring: results from the ROLO randomised control trial

Environmental factors during fetal development can influence variable DNA methylation patterns which have been implicated in the long-term health of the offspring. Maternal diet during pregnancy has been shown to influence offspring DNA methylation at birth but research is limited as to whether these changes persist as the child ages. This study aims to investigate if a dietary invention or other maternal factors during pregnancy have a lasting...