Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases
Abstract
Background and AimsCauses of inflammatory bowel diseases are not well understood and the most prominent forms, Crohn’s disease (CD) and ulcerative colitis (UC), are sometimes hard to distinguish. Glycosylation of IgG has been associated with CD and UC. IgG Fc-glycosylation affects IgG effector functions. We evaluated changes in IgG Fc-glycosylation associated with UC and CD, as well as with disease characteristics in different patient...
Paper Details
Title
Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases
Published Date
Jan 6, 2018
Journal
Volume
154
Issue
5
Pages
1320 - 1333.e10
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