Renal tubular epithelial cells injury induced by mannitol and its potential mechanism
Abstract
Administration of mannitol with high dose could induce extensive isometric renal proximal tubular vacuolization and acute renal failure in clinic. We previously demonstrated that mannitol-induced human kidney tubular epithelial cell (HK-2) injury. The objective of our present work was to further study the cytotoxicity of mannitol in HK-2 cells and its potential mechanism. Cell viability was assessed by an MTT method. Cell morphological changes...
Paper Details
Title
Renal tubular epithelial cells injury induced by mannitol and its potential mechanism
Published Date
Jan 4, 2018
Journal
Volume
40
Issue
1
Pages
85 - 91
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