Oxidative Stress in the Amygdala Contributes to Neuropathic Pain
Abstract
Earlier studies indicate that the central nucleus of the amygdala (CeA) contributes to neuropathic pain. Here we studied whether amygdaloid administration of antioxidants or antagonists of TRPA1 that is among ion channels activated by oxidative stress attenuates nociceptive or affective pain in experimental neuropathy, and whether this effect involves amygdaloid astrocytes or descending serotonergic pathways acting on the spinal 5-HT1A receptor....
Paper Details
Title
Oxidative Stress in the Amygdala Contributes to Neuropathic Pain
Published Date
Sep 1, 2018
Journal
Volume
387
Pages
92 - 103
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