Crossing the blood-brain barrier with nanoparticles

Volume: 270, Pages: 290 - 303
Published: Jan 28, 2018
Abstract
The blood-brain barrier (BBB) is one of the most essential protection mechanisms in the central nervous system (CNS). It selectively allows individual molecules such as small lipid-soluble molecules to pass through the capillary endothelial membrane while limiting the passage of pathogens or toxins. However, this protection mechanism is also a major obstacle during disease state since it dramatically hinders the drug delivery. In recent years,...
Paper Details
Title
Crossing the blood-brain barrier with nanoparticles
Published Date
Jan 28, 2018
Volume
270
Pages
290 - 303
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