Angiotensin Receptor Neprilysin Inhibitor (ARNI) for Heart Failure with Reduced Ejection Fraction – Early Clinical Experience in Institut Jantung Negara

Background: Sacubitril/valsartan (previously known as LCZ696) is in a new class of drug known as angiotensin receptor neprilysin inhibitor (ARNI) for treatment of chronic heart failure with reduced ejection fraction. In PARADIGM-HF, it was superior to ACE inhibitor alone in reducing the risks of death and hospitalization for heart failure. It is available in Malaysia since January...