Effect of DJ-1 Downregulation on the Functions of the First Trimester Extravillous Trophoblasts
Abstract
DJ-1 ( PARK7) has been reported to be causative gene of Parkinson disease and also an oncogene. A loss in DJ-1 function can lead to cell death in neurodegenerative disease, or a gain of it can cause unregulated cell survival in cancer, respectively. DJ-1 protein is known to be expressed mainly in trophoblastic cells in the placenta with increased expression in the first trimester compared to later in term. However, its role in trophoblast...
Paper Details
Title
Effect of DJ-1 Downregulation on the Functions of the First Trimester Extravillous Trophoblasts
Published Date
Sep 1, 2018
Journal
Volume
25
Issue
9
Pages
1436 - 1445
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