Lactational exposure of polychlorinated biphenyls impair Leydig cellular steroidogenesis in F1 progeny rats
Abstract
The present study was aimed to determine the effects of lactational exposure of PCBs (Aroclor 1254) on Leydig cellular steroidogenesis in F1 progeny rats. Lactating dams were orally treated by gavage with different doses of PCBs (1, 2 and 5mg/kg b.wt./day). Male progenies were sacrificed on PND60. Our results demonstrated that exposure to PCBs decreased the body weight, testis weight and anogenital distance (AGD) index in the F1 progeny rats....
Paper Details
Title
Lactational exposure of polychlorinated biphenyls impair Leydig cellular steroidogenesis in F1 progeny rats
Published Date
Jan 1, 2018
Journal
Volume
75
Pages
73 - 85
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